Auflistung nach Schlagwort "Molecular biology"

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  • Biodegradable microsphere-mediated cell perforation in microfluidic channel using femtosecond laser 
    Ishii, Atsuhiro; Ariyasu, Kazumasa; Mitsuhashi, Tatsuki; Heinemann, Dag; Heisterkamp, Alexander; Terakawa, Mitsuhiro (Bellingham, WA : S P I E - International Society for Optical Engineering, 2016)
    The use of small particles has expanded the capability of ultrashort pulsed laser optoinjection technology toward simultaneous treatment of multiple cells. The microfluidic platform is one of the attractive systems that ...
  • Co-transfection of plasmid DNA and laser-generated gold nanoparticles does not disturb the bioactivity of GFP-HMGB1 fusion protein 
    Petersen, Svea; Soller, Jan T.; Wagner, Siegfried; Richter, Andreas; Bullerdiek, Jörn; Nolte, Ingo; Barcikowski, Stephan; Murua Escobar, Hugo (London : Biomed Central, 2009)
    Ultrashort pulsed laser ablation in liquids represents a powerful tool for the generation of pure gold nanoparticles (AuNPs) avoiding chemical precursors and thereby making them especially interesting for biomedical ...
  • Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: Efficiency and cytotoxicity 
    Durán, Maria Carolina; Willenbrock, Saskia; Barchanski, Annette; Müller, Jessika-M.V.; Maiolini, Arianna; Soller, Jan T.; Barcikowski, Stephan; Nolte, Ingo; Feige, Karsten; Murua Escobar, Hugo (London : Biomed Central, 2011)
    Background: Reproducibly high transfection rates with low methodology-induced cytotoxic side effects are essential to attain the required effect on targeted cells when exogenous DNA is transfected. Different approaches and ...
  • Detection of histone modifications in plant leaves 
    Jaskiewicz, Michal; Peterhansel, Christoph; Conrath, Uwe (Cambridge : JOVE, 2011)
    Chromatin structure is important for the regulation of gene expression in eukaryotes. In this process, chromatin remodeling, DNA methylation, and covalent modifications on the amino-terminal tails of histones H3 and H4 ...
  • Double-slit photoelectron interference in strong-field ionization of the neon dimer 
    Kunitski, Maksim; Eicke, Nicolas; Huber, Pia; Köhler, Jonas; Zeller, S.; Voigtsberger, J.; Schlott, Nikolai; Henrichs, Kevin; Sann, H.; Trinter, F.; Schmidt, L.; Kalinin, Anton; Schöffler, M.; Jahnke, T.; Lein, Manfred; Dörner, R. (London : Nature Publishing Group, 2019)
    Wave-particle duality is an inherent peculiarity of the quantum world. The double-slit experiment has been frequently used for understanding different aspects of this fundamental concept. The occurrence of interference ...
  • Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites 
    Höfler, Simone; Lukat, Peer; Blankenfeldt, Wulf; Carlomagno, Teresa ([London] : Macmillan Publishers Limited, part of Springer Nature, 2021)
    Box C/D ribonucleoprotein complexes are RNA-guided methyltransferases that methylate the ribose 2’-OH of RNA. The central ‘guide RNA’ has box C and D motifs at its ends, which are crucial for activity. Archaeal guide RNAs ...
  • The gene space of European mistletoe (Viscum album) 
    Schröder, Lucie; Hohnjec, Natalija; Senkler, Michael; Senkler, Jennifer; Küster, Helge; Braun, Hans-Peter (Oxford [u.a.] : Wiley-Blackwell, 2022)
    European mistletoe (Viscum album) is a hemiparasitic flowering plant that is known for its very special life cycle and extraordinary biochemical properties. Particularly, V. album has an unusual mode of cellular respiration ...
  • Optical and electron microscopy study of laser-based intracellular molecule delivery using peptide-conjugated photodispersible gold nanoparticle agglomerates 
    Krawinkel, Judith; Richter, Undine; Torres-Mapa, Maria Leilani; Westermann, Martin; Gamrad, Lisa; Rehbock, Christoph; Barcikowski, Stephan; Heisterkamp, Alexander (London : BioMed Central Ltd., 2016)
    Background: Cell-penetrating peptides (CPPs) can act as carriers for therapeutic molecules such as drugs and genetic constructs for medical applications. The triggered release of the molecule into the cytoplasm can be ...
  • Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics 
    Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Wögrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Frieß, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Königshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Önder; Burgstaller, Gerald (Washington, DC [u.a.] : Assoc., 2021)
    Fibrogenic processes instigate fatal chronic diseases leading to organ failure and death. Underlying biological processes involve induced massive deposition of extracellular matrix (ECM) by aberrant fibroblasts. We subjected ...
  • PV module current gains due to structured backsheets 
    Vogt, Malte R.; Holst, Hendrik; Schulte-Huxel, Henning; Blankemeyer, Susanne; Witteck, Robert; Bujard, Patrice; Kues, Jan-Bernd; Schinke, Carsten; Bothe, Karsten; Köntges, Marc; Brendel, Rolf (London : Elsevier Ltd., 2017)
    We evaluate the optical performance of PV modules with respect to an increase in short circuit current density. Our evaluation is based on the combination of ray tracing simulations and measurements on test modules with ...
  • Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics 
    Fuchs, Philippe; Rugen, Nils; Carrie, Chris; Elsässer, Marlene; Finkemeier, Iris; Giese, Jonas; Hildebrandt, Tatjana M.; Kühn, Kristina; Maurino, Veronica G.; Ruberti, Cristina; Schallenberg-Rüdinger, Mareike; Steinbeck, Janina; Braun, Hans-Peter; Eubel, Holger; Meyer, Etienne H.; Müller-Schüssele, Stefanie J.; Schwarzländer, Markus (Oxford [u.a.] : Wiley-Blackwell, 2020)
    Mitochondria host vital cellular functions, including oxidative phosphorylation and co-factor biosynthesis, which are reflected in their proteome. At the cellular level plant mitochondria are organized into hundreds of ...